In the question, ARE ANTI-DEPRESSANTS RUINING OUR SEX LIFE?, I have some experience. I am 25, was on Zoloft for about 3 years prior to now (just now got off, which is HELL, but I was able to do it), and this drug just simply made it almost impossible to ejaculate. Sure, I could get an erection and actually perform, but never finish for at least an hour (literally). It was the most frustrating feeling for my wife and I, and since I started tapering off and gradually getting off the anti-depressants, it has done a complete 180. My wife can get me off in 5 minutes, no problem whatsoever now. Things have been basically the same, other than the drug, so put the two together and that basically proves to me (and should to most everyone) that those drugs DO affect the sex drive/performance of males.